Bio-Kult: A Probiotic Supplement with PXN Strains

Bio-Kult is a probiotic supplement with PXN strains

Bio-Kult Advanced Multi-Strain Formula is a multi-strain probiotic supplement marketed for healthy digestive and immune systems. It is manufactured by Probiotics International Ltd. in the UK. The strains used are trademarked as Protexin strains.

There are 4 different formulations of Bio-Kult at the time of this writing, but the emphasis here is on the original adult formulation, the Advanced Multi-Strain Formula.

What Probiotics are in Bio-Kult Advanced Multi-Strain Formula?

This probiotic supplement contains a minimum of 2 billion CFU per capsule of 14 Protexin probiotic strains stated to be proven to survive the low pH of stomach acid including:

  1. Bacillus subtilis PXN21
  2. Bifidobacterium bifidum PXN23
  3. Bifidobacterium breve PXN25
  4. Bifidobacterium infantis PXN27
  5. Bifidobacterium longum PXN30
  6. Lactobacillus acidophilus PXN35
  7. Lactobacillus delbrueckii subsp. bulgaricus PXN39
  8. Lactobacillus casei PXN37
  9. Lactobacillus plantarum PXN47
  10. Lactobacillus rhamnosus PXN54
  11. Lactobacillus helveticus PXN45
  12. Lactobacillus salivarius PXN57
  13. Lactococcus lactis subsp lactis PXN63
  14. Streptococcus thermophilus PXN66

What are the Other Ingredients in Bio-Kult Advanced Multi-Strain Formula? 

The other ingredients at the time of this writing are cellulose as a bulking agent and hydroxypropylmethyl cellulose as the capsule. Traces of milk and soy are present as those are used as the food for the growth of the bacteria.

Please verify ingredients of any supplement prior to taking it.

What is the Recommended Dosage of Bio-Kult Advanced Multi-Strain Formula?

The general recommended serving size on the package is 2 capsules for a total of over 4 billion CFU to maintain your digestive and immune systems.

From the website, recommendations are:

  • 1 - 2 capsules once or twice daily with food. If taking two or more capsules daily, split the dose between two meals.
  • The probiotic capsules can be pulled apart and the contents sprinkled onto cool food, mixed in a cool drink or swallowed whole.
  • If you are taking antibiotics, take 4 capsules daily, ideally at a different time of the day from the antibiotics. Continue taking for at least 2 weeks after completion of the antibiotic course.
  • For travelers, 2 weeks before travel follow guidelines for general use. During travel take 4 capsules daily. Continue to take for at least 2 weeks following the end of travel.
  • Children under 12 should take half the adult dose.

What Does Research Show about Bio-Kult Advanced Multi-Strain Formula?

Coming soon! For more information on the specifics of this probiotic supplement, including details of what studies have shown, download "The Bio-Kult Guide."

What are the Pros of Bio-Kult Advanced Multi-Strain Formula?

The pros of this probiotic supplement as I see them are:

  • It is multi-species.
  • It is marketed for digestive and immune health and based on the research using some components of this supplement, Bio-Kult lives up to that promise.
  • It contains NO gluten, egg, fish, peanuts, shellfish, wheat, yeast, corn, artificial colors, artificial flavors or preservatives.
  • It is non-GMO.
  • Other ingredients are limited.
  • It is shelf-stable, but should be stored in a cool, dry place out of direct sunlight.
  • Potency is guaranteed through the expiration date of the 2-year shelf life if stored under proper conditions.
  • Capsules are packed in individual blister packs.
  • It is produced under cGMP and ISO 9001:2008 standards.
  • The original strains are kept at a culture collection bank for purity and as a reference for genetic identity.
  • Third-party verification ensures that the product meets label claims and contains no contaminants.
  • It is sold in stores and online.

This product has 4.5 out of 5 stars on Amazon.com as of this writing.

Some of the positive reviews from verified purchasers said:

“This has helped, (not cured) my daughters eczema on the back of her legs, she's 11. It was a noticeable difference when we started using it within a day. It's still there, but when we use this at meals, it does help.” – 1/13/16

“Best probiotic I've ever used. Bought these for my son who has GI issues. He's been using for 3 months now and anytime he has diarrhea we up the dose and he's better by the next day. I'm a believer! Would recommend to everyone. I started taking them and giving to all other members of our family.” – 1/1/16

“Immediate results, very pleased. I take mine with a meal. Small capsules, that are easy to swallow…” – 11/25/15

“I was on 1500mg of antibiotics a day that was making me so sick. Added this, twice a day, and I was no longer sick. I cannot say enough great things about it. Highly recommend!!!” – 11/9/15

Some of the negative reviews from verified purchasers said:

“These probiotics definitely did not sit well with me, I've tried them twice now and both times they've caused stomach cramping, diarrhea, and just general queasiness…” – 12/22/15

“my skin felt itchie and the skin behind my ears cracked after using this product.” – 11/4/15

“orded this for my family, and it has been doing it's job well. However, I mostly wanted it for my three year old son. We are on the GAPS diet, working to heal his GUT from a severe casein allergy. He vomits, get's diarrhea, and terrible rashes when he has milk (even sheep and goats milk, too). We gave him very small amounts of Bio Kult to get started, but almost immediately he developed a rash on his chest and back and bottom and his stools became very loose.” – 1/24/15

“I have an overactive immune system with numerous allergies and this was recommended for this problem. It actually made my symptoms worse. A lot of itching at different places on my body and nasal membranes swelled to the point where I could not breathe through my nose. So instead of helping me it exacerbated the problem.” 12/20/14

What are the Cons of Bio-Kult Advanced Multi-Strain Formula?

The cons of this probiotic supplement as I see them are few:

  • Only the total CFU is given. You don't know how much of each species is present so it is impossible to say if this supplement contains the bacteria in amounts equal to the studied amounts and if it should perform like the supplement used in studies and trials.
  • The bacteria are grown on soy and dairy and may contain traces of those allergens (allergy alert!)
  • Compared to other multi-species probiotic supplements, this one contains a lower number of total CFU of at least 2 billion per capsule. However, the study trials were conducted with less than that.

Where to Find Bio-Kult Advanced Multi-Strain Formula?

This probiotic supplement may be ordered in different package sizes from:

Is Bio-Kult Advanced Multi-Strain Formula the Right Supplement for YOU?

If you would like help in determining if this probiotic supplement is right for you, please consider nutritional consultations with me. I spoke with some representatives from Bio-Kult at a nutrition conference and they impressed me with how little selling they had to do since they felt the research said it all.

Thanks to Mika for suggesting a review of this supplement!

One Other Note

If you decide to take this supplement, I would combine the health benefits of it with the benefits provided by:


Other Probiotic Supplement Reviews

To read about my approach to supplement reviews, and about my reviews of other probiotic supplements, click here.


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