BioClinic Naturals Probiotic-Pro12: Is This the Multi You Need?

Probiotic-Pro12

Bioclinic Naturals Probiotic-Pro-12 is a multi-species probiotic supplement with 12 strains of beneficial bacteria.

Probiotic-Pro12 contains at least 18 billion CFU per capsule at manufacturing date and is guaranteed to have a minimum of 12 billion CFU per capsule at expiration date.

Probiotic-Pro12 is intended to be used to contribute to natural healthy gut flora.

BioClinic Naturals are produced in Canada. Two individuals on the scientific advisory board of BioClinic Naturals are well-known and well-respected authorities in the natural medicine field, Dr. Joe Pizzorno, ND and Dr. Michael Murray, ND.

The manufacturing facilities where the supplements are produced are in accordance with Canadian Good Manufacturing Practices {GMP}. The products, practices, and quality control meet or exceed Canadian government’s Natural Health Products Directorate (NHPD) and Canadian Food Inspection Agency (CFIA) regulations and international standards including FDA/USP (US), Korean Government regulations, and the Therapeutic Goods Administration (TGA) of Australia.

One of the very attractive features of this brand is that every ingredient used as a raw material, regardless of the country of origin, is tested in-house for purity, identification (to make sure it is what it is supposed to be), heavy metals, pesticides and other contaminants in accordance with NHPD, FDA and United States Pharmacopoeia (USP) requirements.

Additionally, all of the finished products are tested, too, for various qualities such as physical properties and potency, disintegration, dissolution and weight variation, as well as for microbial contamination, heavy metals and pesticides. (Some companies assume that the ingredients they ordered are the ingredients they use in their formulation and do no testing on the raw ingredients or final products!)

BioClinic Naturals products are said to be used in formal, human clinical trials with their products through the Canadian Center for Functional Medicine, although I could not find any trials using their probiotic formulations on the CCFM website or through a Google search.

Which Beneficial Bacteria and at What Potency
Are In Probiotic-Pro12?

According to their website at the time of this writing, the 12 probiotic strains and their potencies (at the total expiration potency of 12 billion CFU), per capsule, are:

  •    Lactobacillus casei (HA-108)                  3.00 billion CFU
  •    Lactobacillus rhamnosus (HA-111)         1.44 billion CFU
  •    Bifidobacterium breve (HA-129)             1.20 billion CFU
  •    Bifidobacterium longum (HA-135).         1.20 billion CFU
  •    Lactobacillus acidophilus (HA-122)         1.20 billion CFU
  •    Lactobacillus plantarum (HA-119)           1.20 billion CFU
  •    Lactobacillus rhamnosus (HA-114)          1.20 billion CFU
  •    Bifidobacterium bifidum (HA-132)           0.60 billion CFU
  •    Lactobacillus fermentum (HA-179)          0.60 billion CFU
  •    Lactobacillus salivarius (HA-118)             0.12 billion CFU
  •    Lactobacillus paracasei (HA-196)             0.12 billion CFU
  •    Bifidobacterium lactis (HA-194)               0.12 billion CFU

The product suggested dosage is 1 capsule 3 times per day with food, or as directed by a healthcare practitioner.

“HA” strains are from Harmonium International, Inc., in Canada. These strains are also found in various other probiotic supplements, albeit in different mixes and quantities.

What Allergens are Present?

  • As verified by the customer service representative, at this time Probiotic- Pro12 contains soy and milk.
  • The maltodextrin is not guaranteed to be non-GMO corn.
  • Other ingredients, besides the bacteria, at the time of this writing are: Maltodextrin, vegetarian capsule (carbohydrate gum [cellulose], purified water), FOS (fructooligosaccharides) (naturally occurring complex fructose molecules derived from beet sugar or cane sugar), inulin (chicory), vegetable grade magnesium stearate (lubricant), silica, ascorbic acid.
  • Contains no artificial preservatives, colors or sweeteners; no corn, gluten, starch or wheat.

The Pros of Probiotic-Pro12 as I See It

  1. Multiple species of bacteria to help create a village of beneficial microbes
  2. Beneficial bacteria are proven to survive stomach acid and high bile concentrations
  3. At least 12 billion CFU/capsule at time of expiration, and at least 18 billion CFU at time of manufacture
  4. 8 human-origin strains
  5. Information on the specific strains of beneficial bacteria as well as their amounts are provided. I appreciate the transparency of the manufacturer in disclosing this information.
  6. If product is guaranteed to be free of a certain allergen or to be non-GMO, it will say so on the label.
  7. No artificial preservatives
  8. No artificial colors
  9. No sweeteners
  10. Gluten-free
  11. Wheat-free
  12. Corn-free (according to their testing, although maltodextrin is an ingredient)
  13. Stable at room temperature (although I always recommend that you refrigerate probiotics unless the label specifically says not to do so)
  14. Raw ingredients as well as the final product are tested for quality assurance

The CONS of Probiotic-Pro12 In My Opinion

  1. Maltodextrin may be GMO
  2. Not soy-free
  3. Not dairy-free
  4. Contains FOS and inulin as a prebiotic fibers, but those amounts are not disclosed
  5. I couldn’t find any public studies that use this supplement as a whole (which is not that unusual), nor could I find studies on the individual species which occur the most in the product.
  6. Many of the species/strains included in the product are present in low quantities, so if you are looking for a specific effect from those bacteria, their numbers may not be high enough to provide that.

What is Probiotic-Pro12 Used For?

I have been asked it this product will specifically help with vaginal pH issues. It is only marketed to contribute to natural healthy gut flora, and I could not find any studies linking it to vaginal support.

So, although it contains some of the species that are shown to help with vaginal issues, the bacteria of those species may not be the correct strains for the best female support. In addition, the amounts of those species in this product may not be clinically significant for vaginitis. This doesn't mean that Probiotic-Pro12 cannot help with vaginitis; it may be helpful, but there isn't any scientific evidence that I could find to support that conclusion.

More details about vaginal-support probiotics can be found on the bv (bacterial vaginosis) and probiotics page and on the yeast infection treatment and probiotics page.

That being said, however, I believe that anytime the gut environment is improved, that improvement can only help vaginal issues!

Where to Purchase BioClinic Naturals Probiotic-Pro12?

You can find it in my dispensary.

Other Notes

If you decide to take this supplement, I would combine the health benefits of Probiotic-Pro12 with the benefits provided by:

Of course, always check with your doctor if you have any concerns about taking any probiotics product.


Are YOU taking this supplement? What do YOU think? Leave a FB message below or contact us.


Thanks to Caterina for suggesting a review of this probiotic supplement! Please let me know what you think!


Return to page on other probiotic supplements.

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