Lactobacillus rhamnosus is one of several species of probiotic bacteria that has an impressive resume’ of health benefits. This is one species that certainly has some strain-specific health benefits and attributes, so if you are interested in it, you should decide if you need to consume one of the specific strains. Be healthy, yet save money, by choosing the right probiotics for your needs.
Lactobacillus rhamnosus is a facultative anaerobic lactic acid bacterium (see my microbe page) and is frequently isolated from the human gastrointestinal mucosa, starting in the mouth, of healthy individuals. It is also present in the female vagina and urinary tract.
As you have read on pages of this website for other species of probiotics, prior to DNA analysis it was difficult to determine which species a microbe belonged to because the differences in some cases are minor, and this difficulty caused confusion in classifying microbes. Lactobacillus rhamnosus (or L. rhamnosus for short) had a confusing history because it was originally considered to be a subspecies of Lactobacillus casei. And some of its strains were originally thought to be L. fermentum or L. reuteri. Doing research on this species is a bit challenging!
Modern genetic research found it to be a species of its own, with its own benefits, and found that different strains had varied characteristics. The health benefits of the most common strains are discussed on the individual-strain pages at the bottom of this page.
One of the health benefits that seems to be a general L. rhamnosus characteristic is an anti-inflammatory effect. Potent, direct anti-inflammatory activity on human GI tract cells studied in vitro were noticed as long as the probiotic bacteria were alive. Heat-killed or irradiated bacteria did not have the same effect.
The type strain, the strain designated as the representative of the species, is Lactobacillus rhamnosus ATCC 7469. This strain has been shown to translocate from the intestines in mice to the spleen and liver, and has caused rare, but serious infections in severely ill people. Thus, the potential for an infection in immune-system-compromised people exists.
Another concern is that this probiotic species has antibiotic-resistance to kanamycin, not because of transferrable genes, but because of the way the microbe is made. It is just naturally resistant.
Finally, this probiotic microbe is sometimes blamed for being part of the cause of dental cavities because of the acid it produces, even though it produces anti-microbial compounds against pathogenic bacteria. That argument was one of the reasons that some water supplies and most toothpastes are fluoridated.
However, the L. rhamnosus enzyme that is involved in the process of acid production was not sensitive to fluoride in laboratory tests. Therefore, fluoridated toothpaste and fluoridated water has little effect on it.
A better way to maintain a healthy balance of flora in the mouth (and the entire body) is to limit or eliminate sugary and refined foods and drinks and consume probiotic-laden foods and drinks. For more information on the harmful effects of fluoride, see the Fluoride Action Network.
Some strains of L. rhamnosus are marketed as probiotics and/or used in dairy products such as yogurt, cheese and fermented milks. Some strains are used in fermented meat products, fermented dry sausages, and fermented soy cheeses (particularly in southeast Asia). L. rhamnosus ATCC 7469 has many industrial uses. One of those uses is to transform the waste from bioethanol production into animal feed.
Since Lactobacillus rhamnosus strains are naturally found in foods,
consumption of those foods would give you some benefit. For instance, a study
on Parmigiano Reggiano cheese showed that it can have up to 10
million CFU of viable lactic acid bacteria per gram of product when you eat it. What a delicious way to get beneficial bacteria!
And although the strains of L. rhamnosus may vary from cheese producer to cheese producer, the fact that some obscure, currently undocumented strains have acid- and bile tolerance in lab tests means that someday those obscure strains could be classified as probiotics.
And you could be obtaining those obscure strains today just by eating natural, chunk Parmigiano Reggiano cheese! Of course, you can find food products fortified with L. rhamnosus strains and supplements with L. rhamnosus in them, too.
Many strains of L. rhamnosus have been researched, and some of them are radically different than the type strain. So although all L. rhamnosus strains have many things in common, some of them are different enough to have different effects in your body. If you desire a particular effect, be certain to get the correct strain. Some of the most researched strains are listed below:
To go back to the Lactobacillus page, click here.
(References available upon request.)
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Disclaimer: The information contained in this site is educational in nature and is not intended as diagnosis, treatment, prescription or cure for any physical or mental disease, nor is it intended as a substitute for regular medical care. Consult with your doctor regarding any health or medical concerns you may have.
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