Necrotizing enterocolitis (NEC) is a serious gastrointestinal (GI) disorder that frequently affects premature newborns. It results in a highly diseased state, a high rate (nearly 50%) of necessary surgery and has a high rate of mortality, especially in very low-birth weight infants. NEC affects approximately 7.0% of all very low-birth weight infants and carries a death rate greater than 20%.
The exact causes of NEC are unknown, but it is suspected that it is related to multiple factors such as genetic susceptibility, prematurity, formula feeding and gut dysbiosis (disruption in normal flora.) It is known that the immune system in premature babies is immature and dysbiosis may be the factor which accentuates dysregulation of the immune system.
There have been several studies showing the benefits of probiotics for NEC. One study caught my eye. You don’t often hear of Bifidobacterium adolescentis in the media, but in a new study this probiotic showed protective effects against NEC. Research published in January, 2017 used 100 million CFU of B. adolescentis from Livzon, Zhuhai, China in a rat model of NEC.
In this rat study, neonatal rats were divided into 3 groups: surrogate mother-fed, formula fed or formula fed+probiotic. The formula-fed and formula+probiotic groups were exposed to conditions via a well-established NEC model which, indeed, induced NEC. Throughout the experiment, the surrogate-fed rats increased their body weights and the formula+probiotic rats maintained their body weights, but the formula-fed rats lost weight, which is reflective of NEC. Additionally, other symptoms of NEC, including abdominal distention and diarrhea, appeared in the rats that developed NEC, but the formula+probiotic rats had a significantly better survival rate than the formula-only rats.
After sacrifice, the ileum (distal part of the small intestine) of all rats were evaluated and results showed that B. adolescentis significantly decreased the rate of NEC-like intestinal injury.
Conclusions from this study were that B. adolescentis can prevent necrotizing enterocolitis in premature rats and the mechanism may be protection against inflammation.
One takeaway from this study is that if you are pregnant or planning on becoming pregnant, getting your gut microbiome balanced so that your child has a better chance of having a more-balanced gut microbiome is very important. Nutritional consultations with me can help balance your microbiota so that your vaginal environment and breast milk contain beneficial microbes.
Return to health benefits page.
Please, provide a link to this website or share the pages. I provide original, informative content for my readers and you should do the same.
Thanks for visiting this site! If you've enjoyed reading this page or have found the information to be useful to you, please "like", tweet about it, or share it so others can benefit, too.
Sometimes Facebook takes a few seconds for Facebook commenting to load on mobile devices OR Facebook temporarily does not allow comments on a page. If this happens to you, I apologize in advance. Waiting a few seconds or commenting on other pages may work just fine. Thanks for your understanding!
Comment with Disqus (including as a guest), Twitter or Google accounts:
If you are one of my many readers without a Facebook account, you can still comment.
Disclaimer: The information contained in this site is educational in nature and is not intended as diagnosis, treatment, prescription or cure for any physical or mental disease, nor is it intended as a substitute for regular medical care. Consult with your doctor regarding any health or medical concerns you may have.
Subscribe to my monthly newsletter with news you can use to transform your health!
Get some help with weight loss and using cultured foods and drinks with my free report: "A Shocking Meal Plan for Weight Loss" when you sign up for my monthly newsletter, "Nutritionist Notes."
Some competitors of SBI are posting fake negative reviews of SBI. If you are considering creating your own website business, I highly recommend SBI!