Clear-Biotic: The Probiotic Supplement to Clear Acne?

Clear-Biotic is a probiotic supplement marketed for help with acne.

Clear-Biotic is an oral probiotic supplement with added vitamins marketed to:

  • Prevent acne and pimple breakouts
  • Help eliminate facial blemishes and imperfections
  • Improve complexion
  • Help reduce eczema and psoriasis
  • Improves digestion and helps support a healthy immune system

It is sold by Nu-Derm Skin Care. There is no information concerning the location or phone number for Nu-Derm on their website.

The website also says, “It has been proven effective in reducing the severity of other skin conditions such as eczema and dermatitis… has the Best Natural blend of probiotics PROVEN to reduce and prevent Acne with out a prescription.”

What Probiotic Strains and Other Ingredients Are in Clear-Biotic?

No information about which types of microbes in provided on the Nu-Derm website. The information is proprietary. They only say that there are 20 billion CFU/g. If you need help understanding why that number is meaningless, see my page here.

Answers on as to what is in the product say:

The FOS and BioMos are prebiotics. The rice flour and magnesium stearate would be flow agents. Please verify ingredients of any supplement prior to taking it.

What is the Recommended Dosage of Clear-Biotic?

The recommended dosage on the product is 1-4 capsules daily, preferably with a meal.

What Are Some Reviews of Clear-Biotic?

Reviews on are mixed with over three-quarters of 58 reviewers giving it 5 stars:

“...We started using this product about two months ago for my teens acne. We found that when he takes it, it reduces acne outbreaks and redness. You can expect to see some improvements in as little as a week. Clear Biotic will not completely eliminate you acne problems but it will help prevent acne, reduce the redness and severity while improving your complexion.

The use of clear biotic also seems to reduces the amount of Proactiv and antibiotics required.” - February 4, 2015

I first started to use Clear Biotic to reduce the rebound acne I would get after a course of antibiotics. Apparently, the Antibiotics also kill the good bacteria and can make the flare ups worse after they run there course. This product not only helped reduce my flare ups but improved my overall complexion reducing breakouts and redness. I know use it regularly and find myself using less cover up makeup and less topical medications.” - March 2, 2015

Not impressed with this product. The directions say to take 3 caps daily, however, only 60 caps are in the bottle (not a full month). I am in my forties with slight acne and dry skin. It didn't help me with that nor GI. I only took for 1 month but NO difference at all.“- July 13, 2015

What Are the Pros of Clear-Biotic?

The pros of this probiotic supplement as I see them are:

  • It is labeled to be produced in a GMP (Good Manufacturing Practices) facility
  • It has more than one species of lactic acid bacteria
  • Shelf-stable
  • Produced under GMP conditions
  • Prebiotics included to help support the growth of the probiotics in the intestines

What Are the Cons of Clear-Biotic?

The cons of this probiotic supplement as I see them are:

  • The website does not disclose enough information on what exactly is in the product. Saying it is a proprietary probiotics formula with added vitamins A, E, C and B2 is too general for my comfort. I like to know the exact microbes in the product and exactly which forms of vitamins are in there, too. If it has poorly-absorbed forms of vitamins, those vitamins will provide little, if any, benefit.
  • The company does not provide a phone number on the website. They appear to rely on their contact form only.
  • The product is not guaranteed to be free of any common allergens. No information about what is NOT in the product is available.
  • If the answers are correct, then this product contains very low numbers of Lactobacillus and Bifidobacterium species compared to most other multi-species probiotic supplements. One capsule contains only 744 million CFU total. The 20 billion CFU/g number is meaningless.
  • You don't know which strains are in the product since the information is proprietary. It is not possible to predict what effects on acne or digestive health this product will have, or even if the strains are stomach acid- and bile-tolerant strains.
  • It is unknown if the total CFU is at the time of manufacture, or at expiration, so you don't know if you are really getting the amount listed on the label by the time you take it.
  • This probiotic supplement is made with a gelatin capsule (Beef allergy alert!)
  • This supplement contains FOS, a carbohydrate prebiotic to support the growth of the microbes, which may pose problems for some people even though it is at an amount less than 1 gram per 4 capsules.
  • Clear-Biotic contains BioMos, which if it is the same Bio-Mos that I know of, is a prebiotic derived from the cell wall of yeast (usually a strain of Saccharomyces cerevisiae) which contains proteins, lipids, and carbohydrate components, especially mannanoligosaccharides (MOS). Bio-Mos is manufactured by Alltech as an animal feed additive.
  • No studies with this supplement as a whole supplement have been performed to my knowledge. Note that this is not unusual, however. Very few multi-species probiotic supplements are used in studies. Instead, species and strains that are show to be effective are mixed together in most multi-species supplements such as this one. Whether or not the strains compete with each other in a laboratory setting is not known since we don’t know which strains are in it.
  • There is no mention of third-party verification of either the supplies or the finished product to insure that the product is as pure as possible.
  • Sold only online.

Where to Find Clear-Biotic?

Clear-Biotic is only available from at the time of this writing (December, 2015).

Is Clear-Biotic the Right Supplement for YOU?

If you haven't read my pages on acne and probiotics for acne, I encourage you to do that so that you gain an understanding of the roots of your problem.

Clear-Biotic is a probiotic supplement that has "safe" species of Lactobacillus and Bifidobacterium, it is shelf-stable and is produced in a GMP facility. However, it is a very low-potency supplement, with added prebiotic fibers, and that could be the reason for mixed reviews.

I requested more information from Nu-Derm and will update the page when/if I receive that information.

One final thought is that the species of Lactobacillus acidophilus, casei and rhamnosus, and of Bifidobacterium bifidum, are available in many other products besides this one, such as Nutrition Now PB-8 , iFlora and Hyperbiotics PRO-15. The strains may be different, but there is no way to know that without knowing what is in this or the other products. The other products may not have the FOS or Bio-Mos in them, however.

Thanks to Cherubs for suggesting a review of this product!

One Other Note

If you decide to take this supplement, I would combine the health benefits of it with the benefits provided by:

You may also consider nutritional consultations to help you identify your acne triggers and reduce the dysbiosis and inflammation behind the outbreaks.

Other Probiotic Supplement Reviews

To read about my approach to supplement reviews, and about my reviews of other probiotic supplements, click here.

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